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SAG1 protein domain : ウィキペディア英語版 | SAG1 protein domain
In molecular biology, the SAG1 protein domain is an example of a group of glycosylphosphatidylinositol (GPI)-linked proteins named SRSs (SAG1 related sequence). SAG1 is found on the surface of a protozoan parasite ''Toxoplasma gondii''. This parasite infects almost any warm-blooded vertebrate. The surface of ''T. gondii'' is coated with a family of developmentally regulated glycosylphosphatidylinositol (GPI)-linked proteins (SRSs), of which SAG1 is the prototypic member. ==Function== SAG1 and the rest of the SRS protein family mediate cell adhesion to the host cell. They also recognise herapin sulphate proteoglycans, which are part of the Extracellular matrix.
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